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pentobarbital will minimize the extent or influence of diazepam buccal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch. Robust or reasonable CYP3A4 inducers could improve rate of diazepam elimination; hence, efficacy of diazepam may very well be diminished.pentobarbital will reduce the extent or influence of ixabepilon